Lupus erythematosus cells in pleural effusion: the initial manifestation of procainamide-induced lupus erythematosus.
نویسندگان
چکیده
A 63-year-old man developed an asymptomatic pleural effusion following the administration of 500 gm of procainamide hydrochloride over a six-month period. The diagnosis was initially suggested by the finding of lupus erythematosus cells in the pleural fluid. Lupus erythematosus cells and antinuclear antibodies appeared in the blood two months later and remained for a period of six months. The diagnosis was corroborated by the presence of antibodies to denatured DNA, but not to native DNA.
منابع مشابه
Drug-induced lupus erythematosus with in vivo lupus erythematosus cells in pleural fluid.
Pleural involvement in drug-induced lupus erythematosus is not uncommon. Lupus erythematosus cells were found in vivo in the pleural of an elderly patient who had received procainamide (Pronestyl) hydrochloride (2 gm daily) for nine months. Patients who initially have pleural effusions while receiving drugs capable of inducing lupus erythematosus should have the fluid analyzed for lupus erythem...
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عنوان ژورنال:
- Chest
دوره 72 5 شماره
صفحات -
تاریخ انتشار 1977